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“Small Natural Robots”
We’re in an odd spot. For a very long time, our tradition has been assuming that nature is our property and our slave. An unruly and hostile slave — a slave to be tamed, dominated, and abused — so long as we are able to get away with it and be ok with ourselves as we dominate.
A element of that mindset is that human beings are seen by essentially the most highly effective folks in society as their slaves, too. Chances are you’ll be center class and even higher center class … they don’t care. Of their thoughts, you’re their toy, exist for them. And because it goes, regardless of the masters do to nature or to the animals, they do to the folks subsequent.
For instance, as increasingly folks moved to cities, we have been instructed to undertake the behavior of essentially chipping, vaccinating, and neutering our pets. It’s all for their very own good, proper? Nicely, it began with chipping pets however now … I digress.
This story is in regards to the micro organism. After they speak about programmable micro organism or “micro organism with programmable DNA,” I see it as twin risk, On the one hand, I can’t assist however take into consideration the truth that to our masters, human beings on the bottom aren’t any completely different than micro organism. Individuals are a useful resource to them — and they don’t seem to be shy about their need to program organic life, together with human life. That a lot, we all know.
Secondly, we don’t know something in regards to the long-term security of the merchandise produced with genetically modified bugs. And as we speak, genetically modified microbes are a serious and nonetheless rising medium for the commercial manufacturing of chemical substances, meals, medicines, therapeutic proteins, and so forth. And allegedly, producers don’t even have to label such merchandise as GMO.
Bioengineered Meals: An Interlude
“Bioengineered” is the most recent time period for GMO. Here’s a quote from the web page on the U.S. Division of Agriculture web site that accommodates producer FAQs. I’m utilizing their phrases verbatim in order that we are able to get guidelines and definitions straight out of their mouth.
Q: What data are ample to confirm {that a} meals is sourced from a non-bioengineered crop?
• Quite a lot of data could also be ample to confirm a meals is sourced from a non-bioengineered crop. A non-exhaustive checklist contains: natural certification, data that present a non-BE crop selection was used, and data that present a meals originated in an space the place that particular BE meals isn’t produced.
Q: What’s the threshold for bioengineered substance, and the way is it measured?
• The edge is designed to acknowledge the realities of the availability chain and acknowledge that BE and non-BE meals and elements are sometimes grown, harvested, transported, and processed in shut proximity to at least one one other. Due to this actuality, even when a non-BE ingredient is used, there could also be a hint quantity of a BE substance that is still on shared gear.
• The edge exempts meals wherein no ingredient deliberately accommodates a bioengineered substance and permits for the inadvertent or technically unavoidable presence of a BE substance, of as much as 5 %, in every ingredient.
Q: I’m a regulated entity that will qualify for the very small meals producers exemption. How do I calculate my whole income?
• The Normal at 7 CFR 66.5(b) exempts very small meals producers from the BE disclosure necessities. At 7 CFR 66.1, very small meals producers are outlined as any meals producer with annual receipts of lower than $2,500,000 USD.
This quantity contains all meals and non-food receipts. Meals producer is outlined as an entity that manufactures, processes, or packs human meals and labels the meals or meals product for retail sale.
Q. What’s a validated refining course of?
• A validated refining course of is one which has been demonstrated to make modified genetic materials undetectable when adopted. Validation is confirmed by testing and thru upkeep of processing data.
• AMS has revealed a steerage on validation and to pick out a take a look at technique. Each the steerage paperwork and related FAQs will be discovered below detectability testing.
Q. As soon as I’ve validated {that a} refining course of makes modified genetic materials undetectable, do I have to proceed to check that course of?
• No, as soon as a course of has been validated by testing and a regulated entity maintains data displaying the validated course of is adopted, the method doesn’t have to be examined once more except important adjustments are made to that refining course of.
And one other quote:
Q. If a uncooked materials has processing aids that aren’t labeled within the ingredient checklist on our completed product, would that be topic to disclosure below the Normal? For instance, we use a vitamin D that has a corn oil service. We label the vitamin D on our completed product, however not the corn oil. If we all know the vitamin D isn’t a bioengineered meals, does the completed product want a BE disclosure due to the corn oil service?
• The definition of bioengineered meals, at 7 CFR 66.1, excludes incidental components which can be current in meals at an insignificant stage and that shouldn’t have any technical or practical impact within the meals, as described in 21 CFR 101.100(a)(3). Incidental components, when utilized in accordance with this definition, will not be required to be included on the ingredient checklist.
If the corn oil you’re utilizing as a processing assist is taken into account an incidental additive as outlined in 21 CFR 101.100(a)(3), then it doesn’t require a bioengineered meals disclosure.
Are you impressed with these labeling requirements? I’m not.
Precision Fermentation
Precision fermentation is a method wherein microorganisms are genetically reprogrammed to supply particular, personalized molecules that may function new meals elements, industrial chemical substances, therapeutic proteins, vaccines, and so forth. Though the long-term results of such merchandise are unknown, from the trade standpoint, precision fermentation is taken into account helpful as it’s doubtlessly cheaper and extra scalable than producing chemical substances instantly from vegetation, and so forth.
In response to Forbes, it’s a “new meals expertise that’s quickly getting into the mainstream. Merchandise reminiscent of milk protein, animal fat, collagen, honey, lobster, egg whites and extra are receiving tons of of hundreds of thousands of investor {dollars} … These merchandise are being marketed to a younger client base that wishes sustainable, climate-friendly meals that buck the system and promise a greater tomorrow.” Hmmm, however is it so?
“Precision fermentation expertise is a type of artificial biology … that sometimes requires the usage of genetically engineered microorganisms, that are cultivated in brewery-style fermentation tanks. The little critters, often yeast, algae or micro organism, are programmed by a spread of in-vitro nucleic acid strategies reminiscent of CRISPR, gene enhancing or cloning.
They produce or excrete a selected sellable materials, often edible fat or proteins which can be biologically much like animal merchandise. These finish merchandise will be additional processed into elements or completed CPG gadgets.”
“The … new Nationwide Bioengineered Meals Disclosure Normal wouldn’t require these meals to be labeled as GMO as a result of they don’t comprise the genetically engineered organisms, they’re simply produced by them. Such merchandise would subsequently not qualify for Non GMO Undertaking Verification. As a result of some could also be thought-about novel meals, it’s not clear how they are going to be labeled or regulated in Europe.
And since they’re animal-free, they could be thought-about vegan, however will nonetheless have to have the identical allergen labeling as their animal-based counterparts.”
What in regards to the cell tradition medium? Is it actually as impartial and insignificant as we’re led to imagine?? Even Forbes has query. “Is the nutrient bathtub derived from corn or soy, sometimes genetically modified to face up to excessive dosages of herbicides? Are there provide chains in place to offer such nutrient media at scale? […] How a lot waste materials is produced by such microorganisms relative to sellable product?
This contains metabolic wastes, in addition to the leftover steep as soon as the spent microbes and consumable materials have been filtered out. How will such wastes be disposed of and who’s in the end chargeable for it?”
Oh cease asking foolish questions, says the trade. In response to Meals Navigator, in its 2020 report on precision fermentation in dairy, RethinkX predicted that the expertise would make protein manufacturing “5 occasions cheaper by 2030 and 10 occasions cheaper by 2035 than present animal proteins.”
The “promotional brochure” for the merchandise made with precision fermentation would have you ever imagine that they’re pure and secure. Precision fermentation, nevertheless, is “nothing like its pure counterpart … It makes use of genetically engineered microorganisms, reminiscent of yeast and micro organism, which can be fermented in brewery-style tanks below high-tech, pharmaceutical grade sterile situations.
It’s because these cultures are extremely prone to contamination which might damage the whole batch … The long-term outcomes are fully unknown … Nevertheless it’s all serving the underlying agenda, which is whole management and world domination … These faux, ultraprocessed meals give the globalists unprecedented energy and management over human well being, and so they’re utilizing stealthy advertising strategies.”
“Pure Merchandise”
“Pure merchandise” can also be a proper time period to explain a selected sort of metabolite, the secondary metabolite. In response to this Harvard College article, some organisms, reminiscent of vegetation, fungi and micro organism, are in a position to create a category of molecules known as secondary metabolites, or pure merchandise.
Researchers imagine that they play no direct position within the organism’s regular progress or copy as eradicating these molecules from the organism doesn’t lead to speedy dying. Nonetheless, these organisms depend on pure merchandise designed for particular duties, reminiscent of safety towards different organisms or interplay with their very own species.
“As a result of these molecules are made to impact different organisms in varied methods, they are often very helpful as therapeutics. For instance, they can be utilized to kill dangerous micro organism infecting people, and even have an impact instantly on human cells for varied therapeutic functions. The truth is, most of our medicines are literally derived from or impressed by pure merchandise.”
“One necessary use of pure merchandise is antibiotics. Ever for the reason that serendipitous discovery of penicillin in 1928, which was a pure product from fungi that would kill micro organism … Along with antibiotics, many bacterial pure merchandise produce other therapeutic makes use of.
For instance, rapamycin, often known as sirolimus, is made by the micro organism Streptomyces hygroscopicus, and is used clinically as an immunosuppressant, particularly throughout a kidney transplant. Bleomycin, a pure product discovered from Streptomyces verticillus, is a chemotherapy drug used within the therapy for a spread of cancers.”
Industrial Microbiology
Microorganisms play a major position in industrial manufacturing, and new processes involving microbes are being researched as we converse.
For instance, micro organism can doubtlessly “heal” concrete. Researchers on the College of Bathtub are investigating how some species of Bacillus micro organism might be used to make concrete that may “heal” itself.
As a skeptical peasant with no expertise in building, I’m enthusiastic about “therapeutic” concrete however I certainly hope that they take a look at this materials totally to ensure that the spores they search to combine into the concrete don’t “leach” and make every thing round us some form of a GMO spore fest.
Scientific Data Is Restricted
Genetically modified microbes sound nice for the underside line — however do the scientists know in earnest how issues work, and what results in what? Are they positive? If we’re to imagine this paper, they don’t seem to be.
“Regardless of mounting proof linking host-associated micro organism to regular improvement and illness in animal fashions and correlative proof in people, the mechanisms by which particular bacterial features have an effect on mammalian or microbiome physiology (i.e., effector features) stay largely undefined [emphasis mine].
The central dogma of molecular biology, historically outlined because the switch of knowledge from DNA to RNA to protein, stops wanting the final word finish level of a lot of the data circulate in a organic system. In a major fraction of mobile processes, the tip level of knowledge circulate isn’t a protein however is, as a substitute, a small molecule.
That is very true for micro organism which rely closely on low-molecular-weight compounds (i.e., small molecules or pure merchandise) to work together with their environment. The systematic characterization of small molecules produced by human-associated micro organism will undoubtedly be key to deciphering the mechanistic particulars of the position the human microbiome performs in our well being and illness.”
Bacterial Biosensors
In response to a paper titled “Bacterial biosensors: The way forward for analyte detection,” micro organism include lots of sensors — and, per Caroline Ajo-Franklin, Ph.D., a professor of biosciences at Rice College whose artificial biology lab develops microbial biosensors, “these sensors do not simply sense, they [also] inform the micro organism to do one thing.”
The researchers need to “leverage these pure responses to have the micro organism inform us, as people, what they’re seeing [and] what they’re feeling.”
The overall precept of a whole-cell microbial biosensor is to program a cell (sometimes by genetic engineering) to acknowledge and generate a measurable sign in response to a selected molecule. When producing biosensors, scientists “co-opt these responses [with a transducer] in order that as a substitute of getting cells that simply make [products like] efflux pumps, [researchers] engineer them to create a response [the scientists] can learn.”
“Relying on the biosensor and its supposed use, this response will be electrochemical or contain expression of fluorescent or luminescent reporter proteins. Complete-cell biosensors are sometimes engineered to work solely when their goal molecule is current. This capability to fine-tune specificity and sensitivity has made bacterial biosensors promising analytical instruments.”
Complete-cell biosensors can “present perception on nutrient ranges and natural compounds in soils, which may inform strategies for managing crop progress. They’ll additionally sign the presence and ranges of probably problematic compounds.”
“Along with vitamins and poisonous compounds, bacterial biosensors will be designed to answer … different micro organism. Microbes secrete all kinds of metabolites, lots of which might function goal analytes. As an example, microbial biosensors that detect quorum sensing molecules secreted by bacterial pathogens can sign the presence of disease-causing microbes in water, or in human samples to assist diagnose infections.”
“Bacterial biosensors might present helpful intel into the well being of human sufferers. A current research described a biosensor created from the environmental bacterium, Acinetobacter baylyi, that may detect DNA from most cancers cells in vitro and in a mouse mannequin. This research offers a foundation for the appliance of microbial biosensors in most cancers detection and prognosis.
Scientists have additionally created ingestible biosensors that may detect bleeding or inflammatory biomarkers within the intestine to watch intestinal well being; the alerts from these inner microbial units will be transmitted to exterior units, like cellphones, thus illustrating how biosensors will be paired with present digital applied sciences to facilitate knowledge assortment and evaluation.”
My two cents? On the one hand, it’s fantastic to have the ability to detect pollution round us (assuming it really works). It might be fantastic however … however the issue is that as standard, the scientists haven’t any clue about what’ll occur in the long run. Will these so known as “small natural robots” assist with one factor and break ten different issues? And the way will we even clear up? Scientists don’t appear to care. Traders giggle on the very thought. And who might be caught with the invoice? Our our bodies. Us.
Graphene Oxide within the Mind: Yay
Talking of getting no clue, this 2023 paper titled, “Graphene Oxide Attenuates Toxicity of Amyloid-β Aggregates in Yeast by Selling Disassembly and Boosting Mobile Stress Response,” talks about utilizing graphene oxide to assist with Alzheimer’s illness.
What an incredible concept! The method relies on the power of GO nanoflakes to counter the aggregation of misfolded amyloid-β (Aβ) peptides within the mind. However what if these misfolded proteins are the mind’s response to an infection?
In spite of everything, the “infectious” idea of Alzheimer’s illness has been identified for some years, and an infection and ensuing irritation might be distinguished elements in creating AD. Then need? Are we simply going to wash the mind in GO nanoflakes till the individual drops lifeless? To not point out GO toxicity, conductivity, and the Web of Issues. Jeez.
“Alzheimer’s illness (AD) is essentially the most prevalent neurodegenerative illness, with the aggregation of misfolded amyloid-β (Aβ) peptides within the mind being considered one of its histopathological hallmarks. Lately, graphene oxide (GO) nanoflakes have attracted important consideration in biomedical areas resulting from their capability of suppressing Aβ aggregation in vitro.
The mechanism of this helpful impact has not been absolutely understood in vivo. Herein, the affect of GO on intracellular Aβ42 aggregates and cytotoxicity is investigated utilizing yeast Saccharomyces cerevisiae because the mannequin organism. This research finds that GO nanoflakes can successfully penetrate yeast cells and cut back Aβ42 toxicity.
Mixture of proteomics knowledge and follow-up experiments present that GO therapy alters mobile metabolism to will increase mobile resistance to misfolded protein stress and oxidative stress, and reduces quantities of intracellular Aβ42 oligomers. Moreover, GO therapy additionally reduces HTT103QP toxicity within the Huntington’s illness (HD) yeast mannequin.
The findings supply insights for rationally designing GO nanoflakes-based therapies for attenuating cytotoxicity of Aβ42, and doubtlessly of different misfolded proteins concerned in neurodegenerative pathology.”
Need for Management … and Us
It seems like lots of this artificial insanity is pushed by the need to regulate. The need to regulate performs an necessary position in our tradition and in our medical paradigms. All in all, we live below the rule of loopy maniacs who search absolute management! It’s a really distorted, neurotic, joyless rule.
The loopy maniacs — the dominators, the power-seeking psychological sort — have been behind each huge atrocity, each not so nice reset for hundreds of years on finish, each main abuse. And they don’t seem to be letting go.
Sure, I imagine that what’s driving the not so nice reset is need for management. That need has been driving our civilization for fairly some time. It is vitally logical that the individuals who wish to have management search to interchange the pure world with an artificial world. In an artificial world, they will impose their guidelines. An artificial world, they will management — or at the least strive. So what can we do?
I imagine that what we do is keep vigilant, educate ourselves, preserve issues in perspective, and demand on the legitimacy of our love of life. The aspiring masters need us to be afraid and unhappy. They need us to carry our head down and to be slaves. However we’re not slaves! And if we do completely every thing from the place of affection — robust, assured, non-push-over love — we’ll show not simply with our phrases however with our actions that we’re not slaves. As a result of slaves, we’re not.
Concerning the Creator
To seek out extra of Tessa Lena’s work, make sure to try her bio, Tessa Fights Robots.
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